| Date | Opponent | Result |
|---|---|---|
| 2/15 | @Saint Vincent | W 16-8 |
| 2/19 | Adrian | L 12-13 |
| 2/22 | @Allegheny | W 17-5 |
| 2/25 | @25Ohio Wesleyan | L 7-14 |
| 3/1 | Wabash | W 14-4 |
| 3/10 | Franklin & Marshall | L 4-13 |
| 3/12 | @Rhodes | W 14-12 |
| 3/14 | @Hendrix | W 18-4 |
| 3/22 | @Mount Union | W 19-6 |
| 3/26 | Baldwin Wallace | L 7-8 |
| 3/29 | Marietta | W 11-3 |
| 4/1 | @Heidelberg | W 24-2 |
| 4/4 | @Muskingum | W 18-6 |
| 4/9 | Otterbein | W 15-8 |
| 4/12 | @Capital | W 12-4 |
| 4/18 | John Carroll | W 14-7 |
| 4/23 | @Wilmington (OH) | W 25-0 |
| 4/30 | #3 John Carroll 2025 OAC Men's Lacrosse Tournament† | |
| †non-divisional |
| Rank | Name | Rating |
|---|---|---|
| 1 | Colin Willits | 7.26 |
| 2 | Mitchel Luck | 5.59 |
| 3 | Caleb Bennett | 5.03 |
| 4 | Cooper Mulligan | 4.26 |
| 5 | John Hale | 3.93 |
| 6 | Mark Mintzlaff | 3.91 |
| 7 | Alex Reimer | 3.81 |
| 8 | Ian Roy | 3.48 |
| 9 | Jack Chaney | 3.44 |
| 10 | Nathan Flynn | 3.37 |
| 11 | Davis Rice | 2.70 |
| 12 | Eli Ferguson | 2.70 |
| 13 | Ryan Frech | 2.59 |
| 14 | Griffin Bartos | 2.57 |
| 15 | Devin Halliday | 2.48 |
| 16 | Lance Stevenson | 2.44 |
| 17 | Carter Colfack | 2.32 |
| 18 | Jack Wasik | 2.30 |
| 19 | Brady Vette | 2.29 |
| 20 | Ryan Baum | 2.28 |